Figure 4: (a) A CDLE case showed negative c-kit expression in epidermis and dermis; however, hair follicles displayed mild positive c-kit expression (IHC, ×100). Inset photo showed high-power view of the same field (IHC, ×400). (b) A CDLE case showed strong positive c-kit expression in all layers of epidermis. Dermis showed positive c-kit expression in spindle-shaped stromal cells (IHC, ×40). CDLE, chronic discoid lupus erythematosus; IHC, immunohistochemistry.