Figure 2: (a) A case of CDLE showed negative CD34 immunoreactivity in epidermis. Dermis showed positive moderate immunoreactivity for CD34 in spindle-shaped cells (IHC, ×40). (b) A case of CDLE showed positive moderate immunoreactivity of CD34 in interstitial stromal cells adjacent to eccrine ducts with built in control of small blood vessels (IHC, ×400). (c) A case of CDLE showed positive mild immunoreactivity of CD34 diffusely in spindle-shaped stromal cells (IHC ×400). CDLE, chronic discoid lupus erythematosus; IHC, immunohistochemistry.