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ORIGINAL ARTICLE
Year : 2020  |  Volume : 33  |  Issue : 3  |  Page : 987-992

In-phase and out-of-phase MRI: a quantitative method for assessment of nonalcoholic fatty liver disease


1 Department of Radiology, Faculty of Medicine, National Liver Institute, Menoufia University, Menoufia, Egypt
2 Department of Radiology, National Liver Institute, Menoufia University, Menoufia, Egypt

Correspondence Address:
Aya Y Mostafa
Department of Radiology, National Liver Institute, Menoufia University, 1st Settlement, New Cairo 32717, Cairo Governorate
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_79_19

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Objective The objective of this study was to assess the efficacy of MRI in-phase and out-of-phase (IPOP) technique in the diagnosis of nonalcoholic fatty liver disease (NAFLD). Background NAFLD is raising great concern nowadays due to its prevalence. It was routinely diagnosed by liver biopsy, which is a highly invasive procedure; hence, the need for a noninvasive method for diagnosis was required. MRI IPOP technique was introduced to fulfill this role. Patients and methods This prospective study was carried out during the period spanning from July 2016 to December 2017; 50 asymptomatic patients with clinical diagnosis of NAFLD and diffuse hyperechogenicity of the liver by ultrasound underwent MRI of the liver with IPOP technique. Manually placed region of interest and two equations, namely F1 and F2, for determination of the grades of steatosis were used. Results The first equation (F1) revealed one patient (male individual) to have minimal steatosis, 24 patients (17 female individuals, seven male individuals) to have mild steatosis, 22 patients (15 female individuals, seven male individuals) to have moderate steatosis and three patients (two female individuals, one male individual) to have marked steatosis, whereas the second equation (F2) revealed one patient (male individual) to have minimal steatosis, 20 patients (13 female individuals, seven male individuals) to have mild steatosis, 26 patients (19 female individuals, seven male individuals) to have moderate steatosis and three patients (two female individuals, one male individual) to have marked steatosis. Conclusion Liver MRI with IPOP technique can be used rapidly and quantitatively to estimate the liver fat content in patients with NAFLD.


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