Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2020  |  Volume : 33  |  Issue : 2  |  Page : 569-573

Corneal surface changes after cross-linking in patients of keratoconus

1 Department of Ophthalmology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Ophthalmology, Qalyub Ophthalmology Hospital, Qalyubia, Egypt

Correspondence Address:
Ahmed M Abd-Elhamid Akel
15 Elkhalig Elmasry Street, Hadayiq El Kobba, Cairo
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mmj.mmj_192_19

Rights and Permissions

Objectives To evaluate the outcome of the corneal cross-linking procedure regarding their effect on morphological and optical properties of the cornea. Background Cross-linking using ultraviolet A light and riboflavin is a method to stop the progression of keratoconus. The orbscan system has the ability to yield corneal thickness, curvature, and elevation data. Patients and methods The study was carried out on 40 eyes of 30 patients, with a mean age 22.55 ± 3.15 years. All underwent corneal cross-linking.Uncorrected visual acuity and best-corrected visual acuity were assessed. Orbscan's Kmax, thickness at thinnest corneal point and at the center of the cornea, irregularity at 3 and at 5 mm optical zone and topographic astigmatism, were all determined before cross-linking and 6 months after. Results There was improvement of uncorrected visual acuity from 0.21 ± 0.09 to 0.23 ± 0.08 and best-corrected visual acuity from 0.62 ± 0.13 to 0.72 ± 0.10 after 6 months (P < 0.001). Significant decreases after 6 months were found in Kmaxvalue from 48.81 ± 2.05 to 47.83 ± 1.94 D (P < 0.001). There was decrease in thickness at thinnest corneal point and at the corneal center (P < 0.001). Irregularity at 3 mm optical zone and irregularity at 5 mm optical zone showed stability without significant change (P = 1.000 and 0.888, respectively). Corneal astigmatism also showed stability without significant change (P = 0.88). Conclusion Patients with progressive keratoconus appear to have improvements in most of the anterior surface topographic measures.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded21    
    Comments [Add]    

Recommend this journal