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ORIGINAL ARTICLE
Year : 2020  |  Volume : 33  |  Issue : 1  |  Page : 122-126

Assessment of vitamin D in hemodialysis patients


1 Department of Internal Medicine, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
3 Department of Internal Medicine, Shebin El-Kom Fever Hospital, Menoufia, Egypt

Correspondence Address:
Eslam A.M El-Khalifa
El-Batanon, Shebin El-Kom, Menoufia 32717
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_317_18

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Objective To evaluate vitamin D status among our prevalent dialysis population to help rapid treatment and prevent complications. Background Hemodialysis patients have markedly higher rates of severe vitamin D deficiency and reduced ability to convert 25(OH) vitamin D into the active form 1, 25-dihydroxyvitamin D. Patients and methods This cross-sectional study includes 70 patients randomly selected from prevalent dialysis population in Elshohda Hospital in Menoufia, and 20 healthy participants with no chronic illness enrolled as a control group. Their 25(OH) vitamin D level was estimated, and individuals who had 25(OH) vitamin D level less than or equal to 30 ng/ml were considered 25(OH) vitamin D deficient and individuals who had 25(OH) vitamin D level more than 30 ng/ml were considered 25(OH) vitamin D sufficient. Patients were subjected to complete history taking and full clinical examinations, and peripheral blood samples were analyzed for complete blood picture, serum albumin, serum calcium, serum phosphorus, intact parathyroid hormone, and serum 25-hydroxyvitamin D. Results This study showed that 74.3% of patients had 25(OH) vitamin D level less than or equal to 30 ng/ml and 25.7% had 25 (OH) vitamin D level more than 30 ng/ml. The control group showed that 70% had 25(OH) vitamin D level less than 30 ng/ml and 30% had 25(OH) vitamin D more than 30 ng/ml. No significant association was found between 25-hydroxyvitamin D and age, sex, parathyroid hormone, BMI, duration of dialysis, calcium, and phosphorus. Conclusion Our study showed that most of our hemodialysis patients (74.3%) had vitamin D deficiency. This percentage is more than the deficiency in control group. No significant association was found between 25-hydroxyvitamin D and age, sex, intact parathyroid hormone (iPTH), calcium, phosphorus, BMI, and duration of dialysis.


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