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ORIGINAL ARTICLE
Year : 2019  |  Volume : 32  |  Issue : 2  |  Page : 506-510

Evaluation of the role of sucralfate cream in decreasing pain intensity and improving healing following open hemorrhoidectomy: a randomized controlled study


Department of General Surgery, Menoufia University Hospital, Menoufia, Egypt

Correspondence Address:
Yahia M Al Khateeb
Department of General Surgery, Menoufia University Hospital, Menoufia
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_766_17

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Objective The aim was to evaluate the role of sucralfate cream in decreasing postoperative pain intensity and in improving the rate of healing. Background Hemorrhoids are one of the common anorectal complaints. Pain after hemorrhoidectomy is usual and multifactorial. Various topical applications were used to reduce pain from the open wound of hemorrhoidectomy. The aim of this study was to evaluate the role of sucralfate cream in decreasing postoperative pain intensity and in improving the rate of healing. Patients and methods In this prospective cohort study, all enrolled patients (n = 50) were presented to Menoufia University Hospital from May 2016 to December 2016 with third or fourth degree hemorrhoids and indicated for open hemorrhoidectomy. All surgeries were carried out by two consultant surgeons using the same technique. After the end of surgery, the patients were randomly assigned into two groups. Sucralfate group (n = 25) received topical 8% sucralfate cream. The placebo group (n = 25) received topical placebo. Results Postoperative pain at day 1, the mean visual analog scale in the sucralfate group was significantly lower than the placebo group (5.72 vs. 8.20, P < 0.001). After 4 weeks, the degree of wound healing was significantly higher in the sucralfate group (P = 0.0001). Conclusion Sucralfate cream may be effective in reducing postoperative pain associated with open hemorrhoidectomy and it can improve the rate of wound healing.


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