Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2019  |  Volume : 32  |  Issue : 2  |  Page : 397-404

Fluid responsiveness in hemodynamically unstable patients: a systematic review


1 Department of Anesthesia, Faculty of Medicine, Menoufia University, Shebeen El-Kom, Egypt
2 Department of Anesthesia, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Correspondence Address:
Abdallah NA Khattab
El-Gomohorya Street, Menoufia 11711
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_8_18

Rights and Permissions

Objective To evaluate the usefulness of different hemodynamic measurements in the detection of fluid responsiveness (FR) among patients with hemodynamic instability. Backgrounds Close hemodynamic monitoring of unstable patients' response to volume expansion is a central component of intensive care. Previous reports demonstrated that only 50% of patients respond to fluid administration with an increase in stroke volume or cardiac output. Data sources A computer literature search of PubMed, Scopus, and Cochrane Central was conducted. Study selection Records were screened for eligible studies according to the predetermined inclusion criteria. Data extraction Data were extracted and synthesized using standardized tables. Data synthesis Data were synthesized qualitatively, and we did not perform a quantitative data analysis. Findings The present review included 21 studies of moderate to high quality. All included studies found that CVP does neither correlate with intravascular volume nor accurately predict the FR. The included studies showed significant heterogeneity regarding the predictive value of pulse pressure variation and stroke volume variation. Passive leg raising-induced changes in cardiac output or related parameters were highly predictive for FR. Conclusion The current literature suggests that the static measures are not reliable indicators of FR. Dynamic indices are of good predictive value regarding FR. In addition, passive leg raising appears to be the most useful test for predicting FR in hemodynamically unstable adults.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed62    
    Printed6    
    Emailed0    
    PDF Downloaded13    
    Comments [Add]    

Recommend this journal