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ORIGINAL ARTICLE
Year : 2018  |  Volume : 31  |  Issue : 3  |  Page : 871-874

Factors affecting the prognosis of hypertrophic cardiomyopathy disease


1 Department of Cardiology, Faculty of Medicine, Menoufiya University, Menoufiya, Egypt
2 Department of Cardiology, National Heart Institute, Cairo, Egypt

Correspondence Address:
Ahmed Y Salem
Department of Cardiology, National Heart Institute, Cairo
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.248754

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To assess the potential factors affecting the prognosis of hypertrophic cardiomyopathy disease. Medline databases (PubMed, Medscape, HYPERLINK “http://www.sciencedirect.com/”ScienceDirect. EMF-Portal) and all materials available in the Internet from 2000 to 2014, and Topol manual of cardiovascular medicine 4th edition. The initial search presented 30 articles of which 20 met the inclusion criteria. The articles studied the relation between several risk factors and the prognosis of hypertrophic cardiomyopathy. If the studies did not fulfill the inclusion criteria, they were excluded. Study quality assessment included whether ethical approval was gained, eligibility criteria specified, appropriate controls, adequate information, and defined assessment measures. Comparisons were made by structured review with the results tabulated. In total 20 potentially relevant publications were included; They indicate an association between left ventricular outflow tract obstruction, previous cardiac arrest, sustained VT, prolonged or repetitive episodes of nonsustained VT on Holter monitoring , left ventricular wall thickness more than 30mm , family history of sudden cardiac dealth , no change or decrease in the blood pressure with exercise , syncope or near syncope, LA size, occurrence of AF, late gadolinium enhancement by magnetic resonance imaging, and poor prognosis in the terms of morbidity and mortality of hypertrophic cardiomyopathy patients. We found an association between left ventricular outflow tract obstruction, previous cardiac arrest, sustained VT, prolonged or repetitive episodes of nonsustained VT on Holter monitoring, left ventricular wall thickness more than 30mm (thirty millemeters), family history of sudden cardiac death, no change or decrease in the blood pressure with exercise , syncope or near syncope, left atrial size, occurrence of AF, late gadolinium enhancement by magnetic resonance imaging, and poor prognosis in the terms of morbidity and mortality of hypertrophic cardiomyopathy patients.


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