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ORIGINAL ARTICLE
Year : 2016  |  Volume : 29  |  Issue : 2  |  Page : 285-290

Transarterial ethanol ablation of hepatocellular carcinoma with lipiodol–ethanol mixture


1 Department of Diagnostic Radiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Diagnostic Radiology and Interventional, National Liver Institution, Menoufia University, Menoufia, Egypt
3 Department of Diagnostic Radiology, El Menashowy Hospital, Egypt

Correspondence Address:
May S El Safty
Omar Ibn Abd El Aziz, Tanta, 31511
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.192426

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Objective: The aim of the study was to determine the safety and effectiveness of transarterial embolization ablation (TEA) of hepatocellular carcinoma (HCC) with a lipiodol–ethanol mixture. Background: TEA is a new treatment strategy for HCC, and some researchers have reported its effectiveness in HCC. Patients and methods: This study was a prospective cohort study conducted at the National Liver Institute and Faculty of Medicine, Menoufia University, and included 40 patients having unresectable HCCs. At 3 and 6 months after TEA, triphasic computed tomography was performed, and tumor responses were assessed using a modified version of Response Evaluation Criteria in Solid Tumor (mRECIST). Results: Every case was treated. At 3 and 6 months after embolization, contrast computed tomography showed no enhancing lesions. a-Fetoprotein levels were significantly reduced (12.18 ± 15.67) at 6 months after treatment. The partial and complete responses of tumors were 12.5 and 87.5%, respectively, 6 months after treatment. The overall survival rate was 90%. Conclusion: TEA is an effective therapy for patients with unresectable HCC.


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