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ORIGINAL ARTICLE
Year : 2016  |  Volume : 29  |  Issue : 2  |  Page : 234-239

Comparison between different lines of treatment of typhoid fever


1 Department of Internal Medicine, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Correspondence Address:
Asmaa M Mousa Nasr
Shebin El-Kom, Menoufia, 32511
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.192405

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Objective: This study was conducted to evaluate the status in antimicrobial susceptibility patterns of Salmonella typhi obtained from blood culture in Shebin El-Kom Fever Hospital. Background: Enteric fever is a global health problem, and rapidly developing resistance to various drugs makes the situation more alarming. Drug sensitivity in S. enterica typhi and paratyphi A isolated from 60 blood culture-positive cases of enteric fever was tested to determine in-vitro susceptibility pattern of prevalent strains. Materials and methods: Strains isolated from 60 blood culture-positive cases of typhoid and paratyphoid fever over a period of 5 months were studied about their sensitivity patterns to chloramphenicol and ciprofloxacin, and were analyzed. Results: Our study revealed that there was a high sensitivity of S. enterica typhi and paratyphi A to chloramphenicol and ceftriaxone (100%) and resistance to ciprofloxacin (20%). Conclusion: These findings suggest changing patterns of antibiotic resistance in enteric fever with re-emergence of chloramphenicol sensitivity and ciprofloxacin resistance in Shebin El-Kom Fever Hospital, Egypt.


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