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ORIGINAL ARTICLE
Year : 2015  |  Volume : 28  |  Issue : 2  |  Page : 521-524

Osteoporosis in patients with chronic obstructive pulmonary disease


1 Chest Department, Faculty of Medicine, Menoufia University, Menufia
2 Al-Mahalla Chest Hospital, Gharibyia Governorate

Correspondence Address:
Ahmad M Zanfal
Al-Mahalla Al Kobra, Ayash, Gharibyia Governorate 31951

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.163912

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Objectives The aim of the study was to determine the incidence and severity of osteoporosis in chronic obstructive pulmonary disease (COPD) patients at different grades of disease. Background COPD is a widely prevalent disease with high morbidity and mortality and is associated with important pathologies, among which is osteoporosis. However, osteoporosis is often undiagnosed in these patients. Participants and methods This study was conducted on 30 patients with COPD and 10 healthy controls (the control group). They were selected from Al-Mahalla Chest Hospital from April 2012 to March 2013. All participants were subjected to detailed clinical history taking, a thorough clinical examination, plain chest radiography (posteroanterior and lateral views), blood sampling for complete blood picture, erythrocyte sedimentation rate, and serum calcium and phosphates, ventilatory function tests (spirometry), and measurement of bone density using dual-energy X-ray absorptiometry. Results The results of this study revealed highly significant reduction in most ventilatory function tests in the COPD group compared with the control group (P ≤ 0.01). Prevalence of osteoporosis was higher in the COPD group compared with the control group (P ≤ 0.05). Prevalence of osteoporosis increased with increasing severity of COPD (P ≤ 0.05). Conclusion Osteopenia and osteoporosis are more prevalent in COPD patients than in healthy controls and the severity of osteoporosis increases with increasing severity of COPD.


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