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ORIGINAL ARTICLE
Year : 2015  |  Volume : 28  |  Issue : 2  |  Page : 447-452

Study of the role of transcatheter arterial chemoembolization using iodized oil with and without gel foam for the management of hepatocellular carcinoma


1 Department of Tropical Medicine, Faculty of Medicine, Menoufia University, Shebeen El Kom, Egypt
2 Department of Radiology, Faculty of Medicine, Menoufia University, Shebeen El Kom, Egypt

Correspondence Address:
Ayman Abd El-Halim Mohammed El-Gamal
Department of Tropical Medicine, Faculty of Medicine, Menoufia University, Shebeen El Kom
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.163900

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Objective The aim of this study was to determine the effectiveness and safety of transcatheter arterial chemoembolization (TACE) using iodized oil with and without gel foam for the management of hepatocellular carcinoma (HCC). Background HCC is one of the most common malignant diseases worldwide, with an increasing incidence in the industrialized countries. The extensive application of surveillance programs for the early detection of HCC in high-risk patients has increased the number of tumors detected at a subclinical stage as well as those that are responsive to effective treatments. Patients and methods This study was carried out on 40 patients with HCC; of these, 20 patients were treated with TACE by lipiodol and adriamycin, group I, and 20 patients were treated with TACE by lipiodol and adriamycin, followed by gel foam, group II. Results A unique criterion of this study is that all the entire study population of the cirrhotic groups had posthepatitic cirrhosis (hepatitis C virus). After TACE, there was a decrease in tumor size, safe in liver function, and a decrease in α-fetoprotein. Conclusion TACE was safe and effective in the treatment of HCC. We found a trend toward greater survival when gel foam was used as the embolic agent for TACE for HCC, although this was not significant compared with lipiodol.


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