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ORIGINAL ARTICLE
Year : 2014  |  Volume : 27  |  Issue : 3  |  Page : 566-569

The value of diffusion-weighted imaging in prediction of outcome of transient ischemic attacks


1 Department of Neuropscychiatry, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Clinical Radiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Correspondence Address:
Eman S Matar
Department of Neuropscychiatry, Faculty of Medicine, Menoufia University, Yassin Abd El Ghaffar Street, Shebin El Kom, Menoufia
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.145514

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Objective The aim of the study was to study the clinical significance of diffusion-MRI in the prediction of outcome of transient ischemic attacks (TIAs) and its relation to the risk factors and TIA clinical presentations. Background Diffusion-weighted imaging (DWI) observations in TIA patients led to the proposal for a new definition of TIA, which is called the 'tissue-based' TIA definition, so that patients with clinical symptoms of focal brain with acute DWI-lesions, irrespective of the neurological signs duration, had a stroke rather than TIA. Patients and methods The participants in this study were classified into two groups: patient group (group I) and control group (group II) (n = 20) of normal individuals. The patients in group I (n = 35) were those who had had recent TIAs for the first time for whom an initial brain DWI was performed within 48 h after the onset of TIA and a follow-up one 3 months later for those with initial positive DWI. Results Initial DWI lesions were detected in nine (25.7%) patients; it was found that those with TIA duration 1 h or more, with mainly AF or carotid artery stenosis more than 50% and presenting clinically with aphasia or motor manifestations, had lesions on DWI. Conclusion TIA patients with duration of symptoms 1 h or more, atrial fibrillation or carotid artery stenosis more than 50% risk factors, and presenting clinically with motor deficits or aphasia had DWI positivity and thus an increased risk of developing stroke.


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